Hepatoprotective effect of Paeoniae radix via Nrf2 activation
نویسندگان
چکیده
منابع مشابه
Antipyretic activity of Radix paeoniae
The acetone extracts of Radix paeoniae (Paeonaceae) root (100 and 200 mg/kg orally) were tested in brewer's yeast-induced pyrexia in rats to assess their antipyretic activity. The pyrexia in rats was reduced significantly (P < 0.05) compared to that of control. These results indicate that the extracts possess antipyretic properties. The root extract showed significant reduction in normal body t...
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The compounds of Radix Paeoniae Rubra (RPR) were isolated and identified by bioassay-guided method, and antithrombotic effects and mechanism were investigated by the acute blood stasis rat model. The RPR extract was evaluated by APTT, TT, PT, and FIB assays in vitro. Results indicated that RPR extract exhibited the anticoagulant activity. In order to find active compounds, six compounds were is...
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In the present study the capacity of Radix Paeoniae Rubra aqueous extract (RPRAE) as an antioxidant to protect against carbon tetrachloride (CCl(4))-induced oxidative stress and hepatotoxicity in Wistar rats was investigated. Six groups of rats were used. Radix Paeoniae Rubra aqueous extract (100 or 200 or 300 mg/kg of bw) or bifendate (100 mg/kg of bw) were given daily by gavage to the animals...
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The present study provides in vitro and in vivo evaluation of Paeoniae alba Radix (PR) on peripheral nerve regeneration. In the in vitro study, we found the PR caused a marked enhancement of the nerve growth factor-mediated neurite outgrowth from PC12 cells as well as their expression of growth associated protein 43 and synapsin I. In the in vivo study, silicone rubber chambers filled with the ...
متن کاملWound healing activity of aqueous extract of Radix paeoniae root.
Aqueous extract of the roots of Radix paeoniae (Paeonaceae) was screened for wound healing by excision, incision and dead space wound models on Wistar rats. The parameters studied were breaking strength in case of incision wounds, epithelialisation and wound contraction in case of excision wound and granulation tissue dry weight, breaking strength and hydroxyproline content in case of dead spac...
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ژورنال
عنوان ژورنال: The Korea Journal of Herbology
سال: 2016
ISSN: 1229-1765
DOI: 10.6116/kjh.2016.31.1.33.